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Can Endometriosis Cause Cancer? Know the Real Risks Now

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23 June 2025
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Can Endometriosis Cause Cancer? Know the Real Risks Now
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Does endometriosis only mean painful periods and fertility problems? Or is there more behind it? If you’ve ever asked yourself, Can endometriosis cause cancer?, you’re not alone. The fear is real and understandable. Pain that doesn’t go away, odd bleeding patterns, long stretches without answers. These things stick in your mind.

Endometriosis isn’t cancer. But research shows some ties between this condition and certain cancer risks. That doesn’t mean everyone with endometriosis will get cancer. It does mean that you need to understand the risks and know what to look for. Staying informed gives you control. And it helps you make decisions that protect your body and your peace of mind.

Let’s break everything down, what endometriosis really is, how it connects (or doesn’t) to cancer, what types of cancer have been studied in this context, and what signs to watch.

What Is Endometriosis?

Endometriosis happens when cells similar to the ones inside the uterus grow in places they don’t belong. This might be on the ovaries, fallopian tubes, bladder, intestines, or even the pelvic wall. These patches of tissue are still reactive to hormones. So, every month, during your cycle, they swell and bleed, just like the uterine lining would.

But since the blood has nowhere to go, it gets trapped. Over time, this can lead to scar tissue, cysts, inflammation, and pain. Some people live with minor discomfort. Others can’t work, walk, or function during flare-ups.

Here’s how it usually presents:

It mostly affects women between 30 and 40, though symptoms often start earlier. There’s no cure, but treatments help reduce symptoms and improve quality of life.

Is There a Link Between Endometriosis and Cancer?

This is where the question “can endometriosis cause cancer” comes in. And the answer is, it’s complicated.

Endometriosis isn’t cancer. It’s not labeled as a precancerous condition either. But over time, some studies show that endometriosis may increase the risk of developing certain cancers. Especially ovarian cancer. The inflammation and abnormal cell growth might play a role in this shift, though it’s rare.

Still, overall, women with endometriosis have more than 4 times the risk of ovarian cancer than those who don’t have it.

This risk doesn’t mean everyone will get cancer. It just means that if you have endometriosis, especially long-term or in the ovaries, it’s smart to watch your symptoms more closely.

Other potential links are still being studied. Most of the focus has been on ovarian cancer, with much less evidence for other types.

Types of Cancer Linked to Endometriosis

Even though the risk of cancer with endometriosis is low, it’s important to know what kinds are most often mentioned in research.

1. Ovarian Cancer

This is the main cancer seen in connection with endometriosis. Specifically, certain subtypes, like clear cell carcinoma and endometrioid carcinoma, are more common in people who’ve had endometriosis for many years. Some of these cases start as endometriosis-associated ovarian carcinoma (EAOC).

This doesn’t mean endometriosis becomes cancer. It means it might create the kind of long-term environment that lets abnormal cells grow into cancer. Hormones like estrogen may fuel this change.

2. Cervical Cancer

The link here is weaker. Some studies have explored cervical clear cell carcinoma in women with cervical endometriosis, but no strong or proven connection exists. Cervical cancer is most often linked to HPV infection, not endometriosis.

3. Endometrial Cancer

This one sounds like it should be connected. But it isn’t. Endometriosis is not the same as endometrial cancer. They involve different tissues, even though the names sound alike. You might see similar symptoms, like pelvic pain or irregular bleeding, but the causes and risks are not shared.

What Are the Warning Signs of Cancer in Women With Endometriosis?

Here’s the tricky part. Some cancer symptoms overlap with endometriosis symptoms. That makes it easy to miss something serious. If you’ve been living with endometriosis for years, it’s tempting to ignore new pain or fatigue and chalk it up to your condition.

But here’s what you should take seriously:

  • New or increasing pelvic pain that feels different

  • Bloating that doesn’t go away after your period

  • Sudden weight loss without trying

  • Bleeding between periods, especially post-menopause

  • Changes in bowel habits (longer than two weeks)

  • Blood in the stool or urine

  • Constant back pain or pressure in the lower belly

If any of these show up, especially if they’re new or worsening, it’s time to see your doctor. Imaging and blood tests can rule out or catch something early.

Diagnosing Endometriosis vs. Cancer

These two aren’t always easy to tell apart. Here’s a quick comparison of how doctors usually go about finding each one:

Feature

Endometriosis Diagnosis

Cancer Diagnosis

Common Exams

Pelvic exam, medical history

Medical history, physical exam

Imaging

Ultrasound, MRI, sometimes CT

CT, MRI, ultrasound, PET scans

Lab Tests

Not always used, may check hormone levels

Blood work, cancer markers

Surgical Methods

Laparoscopy is gold standard

Biopsy (from tumor or suspected tissue)

Time to Diagnose

Often delayed, takes years for many

Depends on type and stage of cancer

Early Detection Tools

Limited; diagnosis often delayed

Screening available for some cancers (e.g. Pap for cervical)

If you have both risks, endometriosis and a family history of cancer, let your doctor know. That may affect what tests they order and how often they check you.

Different Treatment Options for Endometriosis and Cancer

Treatment for endometriosis is based on your symptoms, your age, and whether you want to get pregnant. Choices include:

  • Hormonal birth control (pill, patch, ring)

  • Hormonal IUD

  • Pain relievers (like NSAIDs)

  • GnRH agonists to stop ovulation

  • Laparoscopy to remove endometrial tissue

  • Hysterectomy, in severe or unresponsive cases

Lifestyle changes like regular movement, less alcohol, and a diet low in inflammatory foods may also help ease symptoms.

Cancer treatment, of course, depends on the type and stage. But it often includes:

If someone has both conditions, their doctor will build a treatment plan that takes both into account. Some therapies for cancer can affect hormones, which may also impact endometriosis.

Steps You Can Take to Lower Your Cancer Risk With Endometriosis

While you can’t erase the chance of cancer completely, some steps can help lower your risk, especially if you live with endometriosis.

  1. Track symptoms closely – Use a journal or app. Changes matter.

  2. Stick to follow-ups – Don’t skip appointments, even if you feel better.

  3. Discuss hormone therapy carefully – Some hormones can increase estrogen, which may feed abnormal cells.

  4. Eat anti-inflammatory foods – Think leafy greens, whole grains, berries, and omega-3 fats.

  5. Avoid smoking – Tobacco raises the chance of multiple cancers.

  6. Exercise regularly – It helps balance hormones and maintain a healthy weight.

  7. Ask about family history – If someone in your family had ovarian or breast cancer, share that with your doctor.

None of these guarantees safety. But they tip the odds in your favor.

Final Thoughts 

To answer the question once more, can endometriosis cause cancer? No, it doesn’t directly cause cancer. But the longer you live with it, the more important it is to stay alert. There is a slightly higher chance of certain cancers, especially ovarian types. That means you don’t ignore symptoms, and you don’t miss follow-ups. You stay informed and proactive.

Endometriosis doesn’t define you. But understanding how it may connect to other risks helps you stay one step ahead. You deserve answers and options that protect your health for the long run.



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