Cancer
Nuclear PHGDH regulates macrophage polarization through transcriptional repression of GLUD1 and GLS2 in breast cancer
IntroductionBreast cancer is the most prevalent malignant tumor type and the leading cause of cancer-related mortality among women globally. This...
Read moreCAR T-cell therapy for relapsed/refractory CD5-positive diffuse large B-cell lymphoma yields more favorable outcomes than standard therapy
CD5-positive (CD5+) diffuse large B-cell lymphoma (DLBCL) represents a special subgroup of DLBCL with a more aggressive disease course and...
Read morePlasma L-aspartic acid predicts the risk of gastric cancer and modifies the primary prevention effect: a multistage metabolomic profiling and Mendelian randomization study
AbstractObjective: Based on multistage metabolomic profiling and Mendelian randomization analyses, the current study identified plasma metabolites that predicted the risk...
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Oncologist Is Humbled, Inspired by His Pancreatic Cancer Patients – Pancreatic Cancer Action Network
Marcus Noel, MD Growing up, Marcus Noel, MD, always enjoyed science – especially biology. He also loved sports and dreamt...
Read moreSenescent macrophages in cancer: roles in tumor progression and treatment opportunities
IntroductionMacrophages play critical roles in the tumor microenvironment (TME), where they influence tumor progression through their remarkable plasticity and environmental...
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Black Americans at Increased Risk for Pancreatic Cancer
Black Americans are more likely to get pancreatic cancer than any other racial or ethnic group. They have the highest...
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This Sheriff’s Cruiser Is Wrapped in More Than Gold
A small county in Idaho is GOING GOLD®! Learn the way YOU can too! On June 2, 2025, the Cassia...
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Gold Ribbon Hero: Nolan O.
Meet Nolan, a courageous acute myelogenous leukemia (AML) warrior. At simply 5 months previous, Nolan started displaying flu-like signs...
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“There Isn’t a World Where Cancer Deserves to Be Credited With Victory.”
Riley’s dad Dave, following chemo, radiation and Whipple surgical procedure. Editor’s Be aware: Riley Cherkes misplaced her dad, Dave, in...
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Elucidating the synergistic roles of CD4+ T and dendritic cells in antitumor immunity
A latest publication by Espinosa-Carrasco et al.1 has illuminated the crucial roles of intratumoral immune triads—a singular cluster of CD4+...
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